Alkyl chlorides
Aobchem 1-(Methylsulfonyl)-4-(trifluoromethyl)benzene | ≥95% | CAS 145963-48-0 | C8H7F3O2S | 500mg
1-(Methylsulfonyl)-4-(trifluoromethyl)benzene | ≥95% | CAS 145963-48-0 | C8H7F3O2S | 500mg
Aobchem 1 2 4-Trichloro-5-methylbenzene | ≥97% | CAS 6639-30-1 | C7H5Cl3 | 1g
1 2 4-Trichloro-5-methylbenzene | ≥97% | CAS 6639-30-1 | C7H5Cl3 | 1g
Aobchem 1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 1g
1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 1g
Apexbio Technology LLC I-CBP 112 1640282-31-0 10mg
I-CBP 112 (CAS 1640282-31-0) is a selective small-molecule inhibitor targeting the bromodomains of CREBBP (CBP) and EP300 two epigenetic regulators involved in transcriptional control In biochemical assays I-CBP 112 demonstrates an IC50 of 170 nM against CREBBP with marked selectivity over other bromodomain-containing proteins such as ATAD2 BAZ2B and members of the BET family In vitro studies indicate that I-CBP 112 does not exhibit significant cytotoxicity in U2OS cells at concentrations up to 50 M Currently this compound is utilized predominantly in cellular and molecular studies to dissect the function of CREBBP/EP300 bromodomains in gene regulation with ongoing use limited to preclinical in vitro research contexts
Apexbio Technology LLC I-CBP 112 1640282-31-0 5mg
I-CBP 112 (CAS 1640282-31-0) is a selective small-molecule inhibitor targeting the bromodomains of CREBBP (CBP) and EP300 two epigenetic regulators involved in transcriptional control In biochemical assays I-CBP 112 demonstrates an IC50 of 170 nM against CREBBP with marked selectivity over other bromodomain-containing proteins such as ATAD2 BAZ2B and members of the BET family In vitro studies indicate that I-CBP 112 does not exhibit significant cytotoxicity in U2OS cells at concentrations up to 50 M Currently this compound is utilized predominantly in cellular and molecular studies to dissect the function of CREBBP/EP300 bromodomains in gene regulation with ongoing use limited to preclinical in vitro research contexts
Medchemexpress LLC Rapastinel Trifluoroacetate | 1435786-04-1 | 98.0% | 527.49 | 50 MG
Rapastinel Trifluoroacetate | 1435786-04-1 | 98.0% | 527.49 | 50 MG
![Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264388.png-250.jpg)
Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG
UC-112 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAP) developed for cellular studies of apoptosis and anticancer activity. It produces cytotoxic and antiproliferative effects across multiple human cancer cell lines and is supplied as a solid or as a DMSO solution for research applications.
- Potent IAP inhibitor with reported cell-assay IC50 = 0.7-3.4 μM.
- Demonstrated activity in PC-3, A-375, M14, and DU-145 cell lines.
- High purity (98.92%) suitable for in vitro studies.
- Molecular formula C22H24N2O2; molecular weight 348.44.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use in apoptosis and anticancer mechanism studies.
Aobchem 2 4 6-Trichloro-1 3-benzenedicarbonitrile | ≥95% | CAS 19861-59-7 | C8HCl3N2 | 1g
2 4 6-Trichloro-1 3-benzenedicarbonitrile | ≥95% | CAS 19861-59-7 | C8HCl3N2 | 1g
Aobchem (3-Ethoxy-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid | 97% | C9H9BF4O3 | 250mg
(3-Ethoxy-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid | 97% | C9H9BF4O3 | 250mg
Aobchem 2 6-Difluoro-3-(2 2 2-trifluoroacetyl)benzonitrile | 97% | CAS 1536911-73-5 | C9H2F5NO | 250mg
2 6-Difluoro-3-(2 2 2-trifluoroacetyl)benzonitrile | 97% | CAS 1536911-73-5 | C9H2F5NO | 250mg
Aobchem (5-Ethoxy-2-fluoro-3-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2707609-65-0 | C10H10F4OS | 500mg
(5-Ethoxy-2-fluoro-3-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2707609-65-0 | C10H10F4OS | 500mg
Aobchem 2 4 6-Trichloro-1 3-benzenedicarbonitrile | ≥95% | CAS 19861-59-7 | C8HCl3N2 | 5g
2 4 6-Trichloro-1 3-benzenedicarbonitrile | ≥95% | CAS 19861-59-7 | C8HCl3N2 | 5g
Aobchem (3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2710879-38-0 | C10H10F4OS | 250mg
(3-Ethoxy-2-fluoro-6-(trifluoromethyl)phenyl)(methyl)sulfane | 95% | CAS 2710879-38-0 | C10H10F4OS | 250mg
Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 100 MG
UC-112 is a survivin and XIAP modulator exhibiting anticancer activity. It functions by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal pathway. This compound also effectively reduces XIAP levels in in vivo tumor models, leading to the activation of caspase-3/7 and caspase-9, and ultimately inducing apoptosis in cancer cells. It is suitable for research on melanoma, prostate cancer, and other cancer-related studies.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9
- Induces cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Alters cell cycle distribution in A375 melanoma cells
- Inhibits human melanoma tumor growth in nude mice